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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1J
All Species:
34.85
Human Site:
S280
Identified Species:
69.7
UniProt:
Q5JR12
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JR12
NP_005158.5
505
54834
S280
Y
V
A
N
A
G
D
S
R
A
I
I
V
R
N
Chimpanzee
Pan troglodytes
XP_513628
505
54871
S280
Y
V
A
N
A
G
D
S
R
A
I
I
V
R
N
Rhesus Macaque
Macaca mulatta
XP_001096598
450
48605
M243
I
E
N
A
F
Q
L
M
D
E
Q
M
A
R
E
Dog
Lupus familis
XP_540335
509
54913
S284
Y
V
A
N
A
G
D
S
R
A
I
I
V
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q149T7
507
55531
S281
Y
V
A
N
A
G
D
S
R
A
I
I
V
R
N
Rat
Rattus norvegicus
Q641Y6
504
55192
S278
Y
V
A
N
A
G
D
S
R
A
I
I
V
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507685
606
67811
F251
I
I
P
M
S
R
E
F
T
P
E
T
E
R
Q
Chicken
Gallus gallus
XP_418000
495
54949
S270
Y
V
A
N
A
G
D
S
R
A
I
I
I
R
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q05AL2
516
56543
S288
Y
V
A
N
A
G
D
S
R
A
L
I
V
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608468
651
72868
S256
Y
V
A
N
A
G
D
S
R
A
V
L
C
Q
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798783
601
66691
S359
Y
V
A
N
A
G
D
S
R
A
I
I
S
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49598
399
43332
E192
D
K
E
V
S
Q
R
E
C
N
L
V
V
N
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
85.5
93.1
N.A.
88.3
88.3
N.A.
56.1
68.5
N.A.
47.2
N.A.
30.8
N.A.
N.A.
36.1
Protein Similarity:
100
100
86.7
96.2
N.A.
91.3
90.6
N.A.
63.2
77
N.A.
62
N.A.
45
N.A.
N.A.
51.2
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
6.6
93.3
N.A.
86.6
N.A.
66.6
N.A.
N.A.
86.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
26.6
100
N.A.
93.3
N.A.
86.6
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
75
9
75
0
0
0
0
75
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% C
% Asp:
9
0
0
0
0
0
75
0
9
0
0
0
0
0
0
% D
% Glu:
0
9
9
0
0
0
9
9
0
9
9
0
9
0
17
% E
% Phe:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
9
0
0
0
0
0
0
0
0
59
67
9
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
9
0
0
0
17
9
0
0
0
% L
% Met:
0
0
0
9
0
0
0
9
0
0
0
9
0
0
0
% M
% Asn:
0
0
9
75
0
0
0
0
0
9
0
0
0
9
50
% N
% Pro:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
17
0
0
0
0
9
0
0
9
9
% Q
% Arg:
0
0
0
0
0
9
9
0
75
0
0
0
0
84
9
% R
% Ser:
0
0
0
0
17
0
0
75
0
0
0
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% T
% Val:
0
75
0
9
0
0
0
0
0
0
9
9
59
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _